Severe dengue is associated with consumption of von Willebrand factor and its cleaving enzyme ADAMTS-13.

• المؤلفون الرئيسيون: Kis Djamiatun (مؤلف), Andre J A M van der Ven (مؤلف), Philip G de Groot (مؤلف), Sultana M H Faradz (مؤلف), D Hapsari (مؤلف), Wil M V Dolmans (مؤلف), Silvie Sebastian (مؤلف), Rob Fijnheer (مؤلف), Quirijn de Mast (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Thrombocytopenia, bleeding and plasma leakage are cardinal features of severe dengue. Endothelial cell activation with exocytosis of Weibel-Palade bodies (WPBs) may play an etiological role in this condition.In a cohort of 73 Indonesian children with dengue hemorrhagic fever (DHF), of which 30 with...