Severe dengue is associated with consumption of von Willebrand factor and its cleaving enzyme ADAMTS-13.
Thrombocytopenia, bleeding and plasma leakage are cardinal features of severe dengue. Endothelial cell activation with exocytosis of Weibel-Palade bodies (WPBs) may play an etiological role in this condition.In a cohort of 73 Indonesian children with dengue hemorrhagic fever (DHF), of which 30 with...
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Main Authors: | , , , , , , , , |
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Format: | Book |
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Public Library of Science (PLoS),
2012-01-01T00:00:00Z.
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A1234.567 |
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