Phenotypic and functional characteristics of monocyte subsets in the blood and bone marrow of Indian subjects with Visceral Leishmaniasis.

• Main Authors: Gulafsha Kausar (Author), Shashi Bhushan Chauhan (Author), Ritirupa Roy (Author), Vimal Verma (Author), Sundaram Pandey (Author), Aziza Niyaz (Author), Jaya Chakravarty (Author), Christian R Engwerda (Author), Susanne Nylen (Author), Rajiv Kumar (Author), Mary E Wilson (Author), Shyam Sundar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Visceral leishmaniasis (VL) is a potentially fatal parasitic infection caused by Leishmania donovani in India. L. donovani is an obligate intracellular protozoan residing mostly in macrophages of the reticuloendothelial system throughout chronic infection. Monocytic phagocytes are critical in the pa...