The iron chelating agent, deferoxamine detoxifies Fe(Salen)-induced cytotoxicity

• Main Authors: Masanari Umemura (Author), Jeong-Hwan Kim (Author), Haruki Aoyama (Author), Yujiro Hoshino (Author), Hidenobu Fukumura (Author), Rina Nakakaji (Author), Itaru Sato (Author), Makoto Ohtake (Author), Taisuke Akimoto (Author), Masatoshi Narikawa (Author), Ryo Tanaka (Author), Takayuki Fujita (Author), Utako Yokoyama (Author), Masataka Taguri (Author), Satoshi Okumura (Author), Motohiko Sato (Author), Haruki Eguchi (Author), Yoshihiro Ishikawa (Author)
• Format: Book
• Published: Elsevier, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Iron-salen, i.e., μ-oxo-N,N'-bis(salicylidene)ethylenediamine iron (Fe(Salen)) was a recently identified as a new anti-cancer compound with intrinsic magnetic properties. Chelation therapy has been widely used in management of metallic poisoning, because an administration of agents that bind me...