Extracellular vesicles of Clonorchis sinensis promote the malignant phenotypes of cholangiocarcinoma via NF-κB/EMT axis.

• Main Authors: Xiaowen Pan (Author), Qing He (Author), Yingxuan Yin (Author), Anyuan Xu (Author), Aoxun Wu (Author), Xueqing Yi (Author), Zifeng Zhong (Author), Yinjuan Wu (Author), Xuerong Li (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clonorchis sinensis infection is an important risk factor for cholangiocarcinoma (CCA). It has been reported that extracellular vesicles (EVs) are involved in the parasite-host interaction, and EVs of C. sinensis (CsEVs) can contribute to biliary injuries and inflammation. However, uncertainty surro...