Hedgehog Pathway Blockade Inhibits Melanoma Cell Growth in Vitro and in Vivo

Hedgehog Pathway Blockade Inhibits Melanoma Cell Growth in Vitro and in Vivo

Previous reports have demonstrated a role for hedgehog signaling in melanoma progression, prompting us to explore the therapeutic benefit of targeting this pathway in melanoma. We profiled a panel of human melanoma cell lines and control melanocytes for altered expression of hedgehog pathway members...

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Main Authors: Eva Hernando (Author), Anna Pavlick (Author), Jiri Zavadil (Author), Judy Zhong (Author), Sung Won Han (Author), Laura Poliseno (Author), Erica Friedman (Author), Miguel F. Segura (Author), Kathryn E. O'Reilly (Author), Eleazar Vega-Saenz de Miera (Author), Iman Osman (Author)
Format: Book
Published: MDPI AG, 2013-11-01T00:00:00Z.
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3rd Floor Main Library

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