Mitochondrial uncoupling in the melanocortin system differentially regulates NPY and POMC neurons to promote weight-loss

Objective: The mitochondrial uncoupling agent 2,4-dinitrophenol (DNP), historically used as a treatment for obesity, is known to cross the blood-brain-barrier, but its effects on central neural circuits controlling body weight are largely unknown. As hypothalamic melanocortin neuropeptide Y/agouti-r...

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Main Authors: Natalie Jane Michael (Author), Stephanie Elise Simonds (Author), Marco van den Top (Author), Michael Alexander Cowley (Author), David Spanswick (Author)
Format: Book
Published: Elsevier, 2017-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available