Mitochondrial uncoupling in the melanocortin system differentially regulates NPY and POMC neurons to promote weight-loss
Objective: The mitochondrial uncoupling agent 2,4-dinitrophenol (DNP), historically used as a treatment for obesity, is known to cross the blood-brain-barrier, but its effects on central neural circuits controlling body weight are largely unknown. As hypothalamic melanocortin neuropeptide Y/agouti-r...
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Main Authors: | Natalie Jane Michael (Author), Stephanie Elise Simonds (Author), Marco van den Top (Author), Michael Alexander Cowley (Author), David Spanswick (Author) |
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Format: | Book |
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Elsevier,
2017-10-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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