Potential Limitations of Bioluminescent Xenograft Mouse Models: A Systematic Review

• Main Authors: Yen Ting Shen (Author), Rashi Asthana (Author), Casper Peeters (Author), Christine Allen (Author), Carlo DeAngelis (Author), Micheline Piquette-Miller (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Bioluminescent imaging (BLI) is a versatile technique that offers non-invasive and real-time monitoring of tumor development in preclinical cancer research. However, the technique may be limited by several factors that can lead to misinterpretation of the data. This review aimed to investig...