A study on the genetic polymorphisms of CYP3A5 among the Orang Asli in Malaysia using a next generation sequencing platform

• Main Authors: Geik Yong Ang (Author), Choo Yee Yu (Author), Richard Johari James (Author), Aminuddin Ahmad (Author), Thuhairah Abdul Rahman (Author), Fadzilah Mohd Nor (Author), Syahrul Azlin Shaari (Author), Adzrool Idzwan Ismail (Author), Lay Kek Teh (Author), Mohd Zaki Salleh (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: CYP3A5 is the predominant sub-family of biotransformation enzymes in the liver and the genetic variations in CYP3A5 are an important determinant of inter-individual and inter-ethnic differences in CYP3A-mediated drug disposition and response. Aim: This study aims to investigate the genet...