Preclinical Evaluation of Nitroxide-Functionalised Ciprofloxacin as a Novel Antibiofilm Drug Hybrid for Urinary Tract Infections

• Main Authors: Sophia Hawas (Author), Jilong Qin (Author), Sandra Wiedbrauk (Author), Kathryn Fairfull-Smith (Author), Makrina Totsika (Author)
• Formato: Libro
• Publicado: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Urinary tract infections (UTIs) are the second most common bacterial infection with high recurrence rates and can involve biofilm formation on patient catheters. Biofilms are inherently tolerant to antimicrobials, making them difficult to eradicate. Many antibiofilm agents alone do not have bacteric...