Computer-Aided Identification of Kinase-Targeted Small Molecules for Cancer: A Review on AKT Protein

• Үндсэн зохиолчид: Erika Primavera (Зохиогч), Deborah Palazzotti (Зохиогч), Maria Letizia Barreca (Зохиогч), Andrea Astolfi (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

AKT (also known as PKB) is a serine/threonine kinase that plays a pivotal regulatory role in the PI3K/AKT/mTOR signaling pathway. Dysregulation of AKT activity, especially its hyperactivation, is closely associated with the development of various human cancers and resistance to chemotherapy. Over th...