Chronic Intermittent Hypoxia Induces Early-Stage Metabolic Dysfunction Independently of Adipose Tissue Deregulation

• Main Authors: Fátima O. Martins (Author), Joana F. Sacramento (Author), Elena Olea (Author), Bernardete F. Melo (Author), Jesus Prieto-Lloret (Author), Ana Obeso (Author), Asuncion Rocher (Author), Paulo Matafome (Author), Emilia C. Monteiro (Author), Silvia V. Conde (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Several studies demonstrated a link between obstructive sleep apnea (OSA) and the development of insulin resistance. However, the main event triggering insulin resistance in OSA remains to be clarified. Herein, we investigated the effect of mild and severe chronic intermittent hypoxia (CIH) on whole...