Whole-exome sequencing in patients with premature ovarian insufficiency: early detection and early intervention

• Main Authors: Hongli Liu (Author), Xiaoli Wei (Author), Yanwei Sha (Author), Wensheng Liu (Author), Haijie Gao (Author), Jin Lin (Author), Youzhu Li (Author), Yaling Tang (Author), Yifeng Wang (Author), Yanlong Wang (Author), Zhiying Su (Author)
• Format: Book
• Published: BMC, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The loss of ovarian function in women, referred to as premature ovarian insufficiency (POI), is associated with a series of concomitant diseases. POI is genetically heterogeneous, and in most cases, the etiology is unknown. Methods Whole-exome sequencing (WES) was performed on DN...