The Effect of Glycemic Control on Endothelial and Cardiac Dysfunction Induced by Red Blood Cells in Type 2 Diabetes

• Main Authors: Ali Mahdi (Author), Tong Jiao (Author), Jiangning Yang (Author), Oskar Kövamees (Author), Michael Alvarsson (Author), Maaria von Heijne (Author), Zhichao Zhou (Author), John Pernow (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Red blood cells (RBCs) from patients with type 2 diabetes mellitus (T2DM) induce endothelial dysfunction and impair cardiac function following ischemia via increase in RBC arginase and oxidative stress. Here, we aimed to elucidate whether the effect of RBC-mediated cardiac impairment following ische...