Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule ¹⁸⁸Re-ZHER2:41071

• Main Authors: Yongsheng Liu (Author), Anzhelika Vorobyeva (Author), Anna Orlova (Author), Mark W. Konijnenberg (Author), Tianqi Xu (Author), Olga Bragina (Author), Annika Loftenius (Author), Erica Rosander (Author), Fredrik Y. Frejd (Author), Vladimir Tolmachev (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HER2-targeted radionuclide therapy might be helpful for the treatment of breast, gastric, and ovarian cancers which have developed resistance to antibody and antibody-drug conjugate-based therapies despite preserved high HER2-expression. Affibody molecules are small targeting proteins based on a non...