Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.

Dengue virus (DENV) infection imposes enormous health and economic burden worldwide with no approved treatment. Several small molecules, including lovastatin, celgosivir, balapiravir and chloroquine have been tested for potential anti-dengue activity in clinical trials; none of these have demonstrat...

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Main Authors: Yadunanda Budigi (Author), Eugenia Z Ong (Author), Luke N Robinson (Author), Li Ching Ong (Author), Kirk J Rowley (Author), Alexander Winnett (Author), Hwee Cheng Tan (Author), Sven Hobbie (Author), Zachary Shriver (Author), Gregory J Babcock (Author), Sylvie Alonso (Author), Eng Eong Ooi (Author)
Format: Book
Published: Public Library of Science (PLoS), 2018-02-01T00:00:00Z.
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