Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo

• Main Authors: Xue-Jia Lin (Author), Jian-Hong Fang (Author), Xiao-Jing Yang (Author), Chong Zhang (Author), Yunfei Yuan (Author), Limin Zheng (Author), Shi-Mei Zhuang (Author)
• Format: Book
• Published: Elsevier, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously found that 19 microRNAs (miRNAs) significantly increased in the sera of hepatocellular carcinoma (HCC) patients. Here, we evaluated whether these miRNAs were secreted by HCC cells and contributed to tumor angiogenesis. High level of miR-210-3p (miR-210) was detected in the exosomes iso...