Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils.

• Hauptverfasser: Shona Wilson (Verfasst von), Frances M Jones (Verfasst von), Hassan K M Fofana (Verfasst von), Aissata Doucouré (Verfasst von), Aly Landouré (Verfasst von), Gachuhi Kimani (Verfasst von), Joseph K Mwatha (Verfasst von), Moussa Sacko (Verfasst von), Birgitte J Vennervald (Verfasst von), David W Dunne (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Schlagworte: article
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IgE specific to worm antigen (SWA) and pre-treatment eosinophil number, are associated with human immunity to re-infection with schistosomes after chemotherapeutic treatment. Treatment significantly elevates circulating IL-5 24-hr post-treatment of Schistosoma mansoni. Here we investigate if praziqu...