Biological Distribution after Oral Administration of Radioiodine-Labeled Acetaminophen to Estimate Gastrointestinal Absorption Function via OATPs, OATs, and/or MRPs

We evaluated the whole-body distribution of orally-administered radioiodine-125 labeled acetaminophen (<sup>125</sup>I-AP) to estimate gastrointestinal absorption of anionic drugs. <sup>125</sup>I-AP was added to human embryonic kidney (HEK)293 and Flp293 cells expressing hum...

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Main Authors: Kakeru Sato (Author), Asuka Mizutani (Author), Yuka Muranaka (Author), Jianwei Yao (Author), Masato Kobayashi (Author), Kana Yamazaki (Author), Ryuichi Nishii (Author), Kodai Nishi (Author), Takeo Nakanishi (Author), Ikumi Tamai (Author), Keiichi Kawai (Author)
Format: Book
Published: MDPI AG, 2023-02-01T00:00:00Z.
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3rd Floor Main Library

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