Application of topical gentamicin ointment in the treatment of Nagashima‐type palmoplantar keratosis in children with a nonsense mutation

• Main Authors: Shan Wang (Author), Zhou Yang (Author), Ying Liu (Author), Huan Zhang (Author), Zongyang Liu (Author), Xiaoling Wang (Author), Ying Li (Author), Haihong Liu (Author), Yonghong Yang (Author), Lin Ma (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Importance Nagashima‐type palmoplantar keratosis (NPPK) is a hereditary dermatosis mostly caused by a nonsense mutation in SERPINB7. Despite the increasing interest in readthrough gentamicin treatment of NPPK, clinical evidence for this treatment is limited. Objective This study aimed to pr...