Influence of Different Populations on Pharmacokinetic Bioequivalence Results: Can We Extrapolate Bioequivalence Results from One Population to Another?

• المؤلفون الرئيسيون: Deniz Ozdin (مؤلف), Murray P. Ducharme (مؤلف), France Varin (مؤلف), Anders Fuglsang (مؤلف), Dina Al-Numani (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Purpose: Over the last 15 years, an ever-increasing proportion of pharmacokinetic bioequivalence studies for European/North American generic submissions appeared to have been conducted in geographical/ethnic populations other than those for which the drug is marketed for. The results of pharmacokine...