Influence of Different Populations on Pharmacokinetic Bioequivalence Results: Can We Extrapolate Bioequivalence Results from One Population to Another?

• Những tác giả chính: Deniz Ozdin (Tác giả), Murray P. Ducharme (Tác giả), France Varin (Tác giả), Anders Fuglsang (Tác giả), Dina Al-Numani (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Purpose: Over the last 15 years, an ever-increasing proportion of pharmacokinetic bioequivalence studies for European/North American generic submissions appeared to have been conducted in geographical/ethnic populations other than those for which the drug is marketed for. The results of pharmacokine...