The Complex of p-Tyr42 RhoA and p-p65/RelA in Response to LPS Regulates the Expression of Phosphoglycerate Kinase 1

• Главные авторы: Oyungerel Dogsom (Автор), Amir Hamza (Автор), Shohel Mahmud (Автор), Jung-Ki Min (Автор), Yoon-Beom Lee (Автор), Jae-Bong Park (Автор)
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• Опубликовано: MDPI AG, 2023-12-01T00:00:00Z.
• Предметы: article
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Inflammation plays a crucial role in tumorigenesis, primarily mediated by NF-κB. RhoA GTPases are instrumental in regulating the activation of NF-κB. Specifically, the phosphorylation of Tyrosine 42 on RhoA ensures the activation of NF-κB by directly activating the IKKβ associated with IKKγ (NEMO)....