Sequential treatment with ursolic acid chlorophenyl triazole followed by 5-fluorouracil shows synergistic activity in small cell lung cancer cells

• Main Authors: Rui-Xia Zhu (Author), Lei Zhao (Author), Yu-Kun Zhang (Author), Peng Luo (Author), Si-Hai Liu (Author), Jin-Guang Wang (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Combination therapy has prolonged the survival of patients with small cell lung cancer (SCLC), an aggressive neoplasm characterized by a high rate of metastasis. In the present study the effect of sequential treatment of ursolic acid chlorophenyl triazole (UACT) followed by 5-fluorouracil (5-FU) on...