Effects of Liposome Clodronate on Renal Leukocyte Populations and Renal Fibrosis in Murine Obstructive Nephropathy

• Main Authors: Koichiro Kitamoto (Author), Yuichi Machida (Author), Junji Uchida (Author), Yasukatsu Izumi (Author), Masayuki Shiota (Author), Takafumi Nakao (Author), Hiroshi Iwao (Author), Tokihito Yukimura (Author), Tatsuya Nakatani (Author), Katsuyuki Miura (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although liposome-encapsulated clodronate has been used as a means to deplete macrophages from certain tissues, target leukocyte subtypes within the kidney are not clearly known under normal and pathologic conditions. The present study was therefore conducted to examine the effects of liposome clodr...