MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients

• Main Authors: Huang Lei (Author), Kufe Donald W (Author), Pelizzari Charles A (Author), Edwards Darrin C (Author), Pitroda Sean P (Author), Khodarev Nikolai N (Author), MacDermed Dhara M (Author), Weichselbaum Ralph R (Author)
• Format: Book
• Published: BMC, 2010-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>MUC1 protein is highly expressed in lung cancer. The cytoplasmic domain of MUC1 (MUC1-CD) induces tumorigenesis and resistance to DNA-damaging agents. We characterized MUC1-CD-induced transcriptional changes and examined their signif...