MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients

• Autori principali: Huang Lei (Autore), Kufe Donald W (Autore), Pelizzari Charles A (Autore), Edwards Darrin C (Autore), Pitroda Sean P (Autore), Khodarev Nikolai N (Autore), MacDermed Dhara M (Autore), Weichselbaum Ralph R (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2010-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>MUC1 protein is highly expressed in lung cancer. The cytoplasmic domain of MUC1 (MUC1-CD) induces tumorigenesis and resistance to DNA-damaging agents. We characterized MUC1-CD-induced transcriptional changes and examined their signif...