Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance

• Main Authors: Marina T. DiStefano (Author), Rachel J. Roth Flach (Author), Ozlem Senol-Cosar (Author), Laura V. Danai (Author), Joseph V. Virbasius (Author), Sarah M. Nicoloro (Author), Juerg Straubhaar (Author), Sezin Dagdeviren (Author), Martin Wabitsch (Author), Olga T. Gupta (Author), Jason K. Kim (Author), Michael P. Czech (Author)
• Format: Book
• Published: Elsevier, 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Adipose tissue relies on lipid droplet (LD) proteins in its role as a lipid-storing endocrine organ that controls whole body metabolism. Hypoxia-inducible Gene 2 (Hig2) is a recently identified LD-associated protein in hepatocytes that promotes hepatic lipid storage, but its role in the a...