Gold Nanoparticles Modified With Polyethyleneimine Disturbed the Activity of Drug-Metabolic Enzymes and Induced Inflammation-Mediated Liver Injury in Mice

• Main Authors: Hanqing Chen (Author), Shuang Zhou (Author), Meilin Zhu (Author), Bing Wang (Author), Wei Chen (Author), Lingna Zheng (Author), Meng Wang (Author), Weiyue Feng (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Gold nanoparticles (GNPs) have been used as a potential bioactive platform for drug delivery due to their unique optical and thermal characteristics. Liver is the main organ in orchestrating physiological homeostasis through metabolization of drugs and detoxification of exogenous substances. Therefo...