High-Dose Cyclophosphamide Administration Orchestrates Phenotypic and Functional Alterations of Immature Dendritic Cells and Regulates Th Cell Polarization

• Główni autorzy: Lei Bao (Autor), Changfu Hao (Autor), Juan Wang (Autor), Di Wang (Autor), Youliang Zhao (Autor), Yiping Li (Autor), Wu Yao (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

High-dose cyclophosphamide (CTX) inhibits the immune response. Dendritic cells (DCs) are professional antigen presenting cells (APCs) with a crucial role in initiating immune responses and sustaining immune tolerance. The relative contribution of DCs to immunosuppression induced by high-dose CTX is...