Enhanced Tailored MicroRNA Sponge Activity of RNA Pol II-Transcribed TuD Hairpins Relative to Ectopically Expressed ciRS7-Derived circRNAs

• প্রধান লেখক: Anne Kruse Hollensen (লেখক), Sofie Andersen (লেখক), Karina Hjorth (লেখক), Rasmus O. Bak (লেখক), Thomas B. Hansen (লেখক), Jørgen Kjems (লেখক), Lars Aagaard (লেখক), Christian Kroun Damgaard (লেখক), Jacob Giehm Mikkelsen (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2018-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

As key regulators of gene expression, microRNAs (miRNAs) have emerged as targets in basic experimentation and therapy. Administration of DNA-encoded RNA molecules, targeting miRNAs through base pairing, is one viable strategy for inhibiting specific miRNAs. A naturally occurring circular RNA (circRN...