Absorption Kinetics of Subcutaneously Administered Ceftazidime in Hypoperfused Guinea Pigs

• Main Authors: Tsuyoshi Ebihara, MS (Author), Shinji Oshima, PhD (Author), Mitsuyoshi Okita, MS (Author), Sayumi Shiina, MS (Author), Akio Negishi, BS (Author), Kousuke Ohara, BS (Author), Shigeru Ohshima, PhD (Author), Hiroyuki Iwasaki, MD (Author), Akira Yoneyama, MD (Author), Eiji Kitazumi, MD (Author), Daisuke Kobayashi, PhD (Author)
• Format: Book
• Published: Elsevier, 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Pneumonia is the most common cause of death in patients with severe motor and intellectual disabilities (SMID), and intravenous ceftazidime (CAZ) is a widely used treatment for such infections. However, intravenous administration in patients with SMID may be difficult because of insuffic...