Identification of Aberrantly Expressed Genes during Aging in Rat Nucleus Pulposus Cells

• Main Authors: Shi Cheng (Author), Xiaochuan Li (Author), Linghan Lin (Author), Zhiwei Jia (Author), Yachao Zhao (Author), Deli Wang (Author), Dike Ruan (Author), Yu Zhang (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nucleus pulposus cells (NPCs) play a vital role in maintaining the homeostasis of the intervertebral disc (IVD). Previous studies have discovered that NPCs exhibited malfunction due to cellular senescence during disc aging and degeneration; this might be one of the key factors of IVD degeneration. T...