N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature

• Main Authors: Phiwayinkosi V. Dludla (Author), Bongani B. Nkambule (Author), Sithandiwe E. Mazibuko-Mbeje (Author), Tawanda M. Nyambuya (Author), Fabio Marcheggiani (Author), Ilenia Cirilli (Author), Khanyisani Ziqubu (Author), Samukelisiwe C. Shabalala (Author), Rabia Johnson (Author), Johan Louw (Author), Elisabetta Damiani (Author), Luca Tiano (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Impaired adipose tissue function and insulin resistance remain instrumental in promoting hepatic lipid accumulation in conditions of metabolic syndrome. In fact, enhanced lipid accumulation together with oxidative stress and an abnormal inflammatory response underpin the development and severity of...