Tricaprylin‐based drug crystalline suspension for intramuscular long‐acting delivery of entecavir with alleviated local inflammation

• Main Authors: Min Young Jeong (Author), Myoung Jin Ho (Author), Joon Soo Park (Author), Hoetaek Jeong (Author), Jin Hee Kim (Author), Yong Jin Jang (Author), Doe Myung Shin (Author), In Gyu Yang (Author), Hye Rim Kim (Author), Woo Heon Song (Author), Sangkil Lee (Author), Seh Hyon Song (Author), Yong Seok Choi (Author), Young Taek Han (Author), Myung Joo Kang (Author)
• Format: Knjiga
• Izdano: Wiley, 2024-07-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract In order to ensure prolonged pharmacokinetic profile along with local tolerability at the injection site, tricaprylin‐based drug crystalline suspension (TS) was designed and its local distribution, pharmacokinetics, and inflammatory response, were evaluated with conventional aqueous suspens...