Methamphetamine Preconditioning Causes Differential Changes in Striatal Transcriptional Responses to Large Doses of the Drug

• Main Authors: Jean Lud Cadet (Author), Christie Brannock (Author), Bruce Ladenheim (Author), Michael T. McCoy (Author), Genevieve Beauvais (Author), Amber B. Hodges (Author), Elin Lehrmann (Author), William H. Wood (Author), Kevin G. Becker (Author), Irina N. Krasnova (Author)
• Format: Book
• Published: SAGE Publishing, 2011-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Methamphetamine (METH) is a toxic drug of abuse, which can cause significant decreases in the levels of monoamines in various brain regions. However, animals treated with progressively increasing doses of METH over several weeks are protected against the toxic effects of the drug. In the present stu...