Adipocyte progenitor cells initiate monocyte chemoattractant protein-1-mediated macrophage accumulation in visceral adipose tissue

• Main Authors: Jennifer L. Kaplan (Author), Melissa A. Marshall (Author), Chantel C. McSkimming (Author), Daniel B. Harmon (Author), James C. Garmey (Author), Stephanie N. Oldham (Author), Peter Hallowell (Author), Coleen A. McNamara (Author)
• Format: Book
• Published: Elsevier, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Macrophages are important producers of obesity-induced MCP-1; however, initial obesity-induced increases in MCP-1 production precede M1 macrophage accumulation in visceral adipose tissue (VAT). The initial cellular source of obesity-induced MCP-1 in vivo is currently unknown. Preliminary...