Association between altered taste perceoption and nutritional outcomes among hemodialysis patients

Taste impairment is prevalent among patients with end-stage renal disease and may compromise nutritional status. There have been no studies examining altered taste perception and nutritional outcomes. We performed a post-hoc analysis of data from the HEMO Study (n=1745). Taste perception was assesse...

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Main Authors: Katherine Lynch (Author), Rebecca Lynch (Author), Gary Curhan (Author)
Format: Book
Published: The Korean Society of Nephrology, 2012-06-01T00:00:00Z.
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Summary:Taste impairment is prevalent among patients with end-stage renal disease and may compromise nutritional status. There have been no studies examining altered taste perception and nutritional outcomes. We performed a post-hoc analysis of data from the HEMO Study (n=1745). Taste perception was assessed at baseline and then updated annually. Time-updated linear and logistic regression models were used to examine the nutritional impact of altered taste perception and to evaluate predictors of altered taste perception. At baseline, 34.6% reported altered taste perception, which was associated with poorer nutritional indices. On longitudinal analysis, altered taste perception was independently associated with a persistently greater need for nutritional supplementation and subsequent reductions in serum albumin (-0.03 g/dL; p=0.02), serum creatinine (-0.22 mg/dL; p=0.009), normalized protein catabolic rate (-0.05; p < 0.001), protein intake (-0.04= g/kg/day; p=0.006), sodium intake (-90 mg/day; p=0.02), and mid-arm muscle circumference (-0.29 cm; p=0.05). Among prevalent hemodialysis patients, altered taste perception was found to be associated with poorer indices of nutritional status at baseline as well as subsequent decline in nutritional indices over time
Item Description:2211-9132
10.1016/j.krcp.2012.04.468