Novel Cyclic Peptides for Targeting EGFR and EGRvIII Mutation for Drug Delivery

• Main Authors: Olga Furman (Author), Alisa Zaporozhets (Author), Dror Tobi (Author), Andrii Bazylevich (Author), Michael A. Firer (Author), Leonid Patsenker (Author), Gary Gellerman (Author), Bat Chen R. Lubin (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The epidermal growth factor-epidermal growth factor receptor (EGF-EGFR) pathway has become the main focus of selective chemotherapeutic intervention. As a result, two classes of EGFR inhibitors have been clinically approved, namely monoclonal antibodies and small molecule kinase inhibitors. Despite...