Integrative Approach for Designing Novel Triazole Derivatives as α-Glucosidase Inhibitors: QSAR, Molecular Docking, ADMET, and Molecular Dynamics Investigations

• Main Authors: Oussama Abchir (Author), Meriem Khedraoui (Author), Hassan Nour (Author), Imane Yamari (Author), Abdelkbir Errougui (Author), Abdelouahid Samadi (Author), Samir Chtita (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In response to the increasing prevalence of diabetes mellitus and the limitations associated with the current treatments, there is a growing need to develop novel medications for this disease. This study is focused on creating new compounds that exhibit a strong inhibition of alpha-glucosidase, whic...