Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine

Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine

<p>Abstract</p> <p>L-acetylcarnitine (LAC), a drug utilized for the treatment of neuropathic pain in humans, has been shown to induce analgesia in rodents by up-regulating the expression of metabotropic glutamate receptor 2 (mGlu2) in dorsal root ganglia (DRG). We now report that L...

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Main Authors: Nicoletti Ferdinando (Author), Morales Maria Elena P (Author), De Petris Laura (Author), Copani Agata (Author), Chiechio Santina (Author), Gereau Robert W (Author)
Format: Book
Published: SAGE Publishing, 2006-06-01T00:00:00Z.
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3rd Floor Main Library

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