Human Host Defense Peptide LL-37 Suppresses TNFα-Mediated Matrix Metalloproteinases MMP9 and MMP13 in Human Bronchial Epithelial Cells
Introduction: TNFα-inducible matrix metalloproteinases play a critical role in the process of airway remodeling in respiratory inflammatory disease including asthma. The cationic host defense peptide LL-37 is elevated in the lungs during airway inflammation. However, the impact of LL-37 on TNFα-driv...
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Main Authors: | Anthony Altieri (Author), Courtney Lynn Marshall (Author), Padmanie Ramotar (Author), Dylan Lloyd (Author), Mahadevappa Hemshekhar (Author), Victor Spicer (Author), Anne M. van der Does (Author), Neeloffer Mookherjee (Author) |
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Format: | Book |
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Karger Publishers,
2024-03-01T00:00:00Z.
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