The Effect of Glutathione Peroxidase-1 Knockout on Anticancer Drug Sensitivities and Reactive Oxygen Species in Haploid HAP-1 Cells

• Main Authors: Steven Behnisch-Cornwell (Author), Lisa Wolff (Author), Patrick J. Bednarski (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2020-12-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The role of glutathione peroxidases (GPx) in cancer and their influence on tumor prognosis and the development of anticancer drug resistance has been extensively and controversially discussed. The aim of this study was to evaluate the influence of GPx1 expression on anticancer drug cytotoxicity. For...