Model‐based simulation to support the approval of isatuximab alone or with dexamethasone for the treatment of relapsed/refractory multiple myeloma in Japanese patients

Model‐based simulation to support the approval of isatuximab alone or with dexamethasone for the treatment of relapsed/refractory multiple myeloma in Japanese patients

Abstract This study aimed to support dosing regimen selection for isatuximab as a single agent or in combination with dexamethasone for Japanese patients with relapsed/refractory multiple myeloma (RRMM). A joint model characterizing the dynamics of serum M‐protein kinetics and its association with p...

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Main Authors: Hoai‐Thu Thai (Author), Kimiko Koiwai (Author), Yoshihisa Shitara (Author), Hirotaka Kazama (Author), Jean‐Baptiste Fau (Author), Dorothée Semiond (Author), Christine Veyrat‐Follet (Author)
Format: Book
Published: Wiley, 2023-12-01T00:00:00Z.
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