Model‐based simulation to support the approval of isatuximab alone or with dexamethasone for the treatment of relapsed/refractory multiple myeloma in Japanese patients

• প্রধান লেখক: Hoai‐Thu Thai (লেখক), Kimiko Koiwai (লেখক), Yoshihisa Shitara (লেখক), Hirotaka Kazama (লেখক), Jean‐Baptiste Fau (লেখক), Dorothée Semiond (লেখক), Christine Veyrat‐Follet (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2023-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract This study aimed to support dosing regimen selection for isatuximab as a single agent or in combination with dexamethasone for Japanese patients with relapsed/refractory multiple myeloma (RRMM). A joint model characterizing the dynamics of serum M‐protein kinetics and its association with p...