Model‐based simulation to support the approval of isatuximab alone or with dexamethasone for the treatment of relapsed/refractory multiple myeloma in Japanese patients

• मुख्य लेखकों: Hoai‐Thu Thai (लेखक), Kimiko Koiwai (लेखक), Yoshihisa Shitara (लेखक), Hirotaka Kazama (लेखक), Jean‐Baptiste Fau (लेखक), Dorothée Semiond (लेखक), Christine Veyrat‐Follet (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2023-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract This study aimed to support dosing regimen selection for isatuximab as a single agent or in combination with dexamethasone for Japanese patients with relapsed/refractory multiple myeloma (RRMM). A joint model characterizing the dynamics of serum M‐protein kinetics and its association with p...