Tadalafil-loaded PLGA microspheres for pulmonary administration: preparation and evaluation
Tadalafil, a long-acting PED-5 inhibitor, is commonly used for the treatment of pulmonary arterial hypertension (PAH). However, its efficacy and clinical application are severely limited by the poor water solubility, low bioavailability and a series adverse effects (e.g. headaches, indigestion). In...
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Format: | Book |
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Universidade de São Paulo,
2019-12-01T00:00:00Z.
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A1234.567 |
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