Expression Analysis of α5 Integrin Subunit Reveals Its Upregulation as a Negative Prognostic Biomarker for Glioblastoma

• Main Authors: Nelly Etienne-Selloum (Author), Julien Prades (Author), Diana Bello-Roufai (Author), Mathieu Boone (Author), Henri Sevestre (Author), Stéphanie Trudel (Author), Pascal Caillet (Author), Alexandre Coutte (Author), Christine Desenclos (Author), Jean-Marc Constans (Author), Sophie Martin (Author), Laurence Choulier (Author), Bruno Chauffert (Author), Monique Dontenwill (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Integrin α5β1 was suggested to be involved in glioblastoma (GBM) aggressiveness and treatment resistance through preclinical studies and genomic analysis in patients. However, further protein expression data are still required to confirm this hypothesis. In the present study, we investigated by immu...