Central nervous system involvement in acute lymphoblastic leukemia: diagnosis by immunophenotyping

• Main Authors: Camila Silva Peres Cancela (Author), Mitiko Murao (Author), Marcelo Eduardo de Lima Souza (Author), José Márcio Barcelos (Author), Vírginia Miguel Furtado (Author), Maria Luiza Silva (Author), Marcos Borato Viana (Author), Benigna Maria de Oliveira (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2013-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The central nervous system is the most commonly affected extramedullary site in acute lymphoblastic leukemia. Although morphologic evaluation of the cerebrospinal fluid has been traditionally used for diagnosing central nervous system involvement, it is a method of low sensitivity. The present study...