Central nervous system involvement in acute lymphoblastic leukemia: diagnosis by immunophenotyping

The central nervous system is the most commonly affected extramedullary site in acute lymphoblastic leukemia. Although morphologic evaluation of the cerebrospinal fluid has been traditionally used for diagnosing central nervous system involvement, it is a method of low sensitivity. The present study...

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Main Authors: Camila Silva Peres Cancela (Author), Mitiko Murao (Author), Marcelo Eduardo de Lima Souza (Author), José Márcio Barcelos (Author), Vírginia Miguel Furtado (Author), Maria Luiza Silva (Author), Marcos Borato Viana (Author), Benigna Maria de Oliveira (Author)
Format: Book
Published: Sociedade Brasileira de Patologia Clínica, 2013-08-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Camila Silva Peres Cancela  |e author 
700 1 0 |a Mitiko Murao  |e author 
700 1 0 |a Marcelo Eduardo de Lima Souza  |e author 
700 1 0 |a José Márcio Barcelos  |e author 
700 1 0 |a Vírginia Miguel Furtado  |e author 
700 1 0 |a Maria Luiza Silva  |e author 
700 1 0 |a Marcos Borato Viana  |e author 
700 1 0 |a Benigna Maria de Oliveira  |e author 
245 0 0 |a Central nervous system involvement in acute lymphoblastic leukemia: diagnosis by immunophenotyping 
260 |b Sociedade Brasileira de Patologia Clínica,   |c 2013-08-01T00:00:00Z. 
500 |a 1678-4774 
500 |a 10.1590/S1676-24442013000400005 
520 |a The central nervous system is the most commonly affected extramedullary site in acute lymphoblastic leukemia. Although morphologic evaluation of the cerebrospinal fluid has been traditionally used for diagnosing central nervous system involvement, it is a method of low sensitivity. The present study aimed at evaluating the use of immunophenotyping in the detection of blasts in the cerebrospinal fluid from children and adolescents with acute lymphoblastic leukemia. 
546 |a EN 
690 |a leucemia linfoide aguda 
690 |a sistema nervoso central 
690 |a líquido cefalorraquidiano 
690 |a imunofenotipagem 
690 |a Pathology 
690 |a RB1-214 
655 7 |a article  |2 local 
786 0 |n Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 49, Iss 4, Pp 260-263 (2013) 
787 0 |n http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000400005&lng=en&tlng=en 
787 0 |n https://doaj.org/toc/1678-4774 
856 4 1 |u https://doaj.org/article/daa7f9b4db7c4a4ca131a447ec1d43f7  |z Connect to this object online.