Reduced Numbers and Impaired Function of Regulatory T Cells in Peripheral Blood of Ischemic Stroke Patients

• Main Authors: Johanna Ruhnau (Author), Juliane Schulze (Author), Bettina von Sarnowski (Author), Marie Heinrich (Author), Sönke Langner (Author), Christian Pötschke (Author), Anika Wilden (Author), Christof Kessler (Author), Barbara M. Bröker (Author), Antje Vogelgesang (Author), Alexander Dressel (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Purpose. Regulatory T cells (Tregs) have been suggested to modulate stroke-induced immune responses. However, analyses of Tregs in patients and in experimental stroke have yielded contradictory findings. We performed the current study to assess the regulation and function of Tregs in...